Publications by Golub Capital Social Impact Lab

Browse or search publications from faculty affiliated with the lab.

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Journal Article

Association of α1-Blocker Receipt With 30-Day Mortality and Risk of Intensive Care Unit Admission Among Adults Hospitalized With Influenza or Pneumonia in Denmark

R.W. Thomsen, C.F. Christiansen, U. Heide-Jørgensen, J.T. Vogelstein, B. Vogelstein, C. Bettegowda, S. Tamang, Susan Athey, H.T. Sørensen
JAMA Network Open February102021

Alpha 1–adrenergic receptor blocking agents (α1-blockers) have been reported to have protective benefits against hyperinflammation and cytokine storm syndrome, conditions that are associated with mortality in patients with coronavirus disease…

Journal Article

Policy Learning with Observational Data

Susan Athey, Stefan Wager
Econometrica January2021 Vol. 89 Issue 1

In many areas, practitioners seek to use observational data to learn a treatment assignment policy that satisfies application-specific constraints, such as budget, fairness, simplicity, or other functional form constraints. For example,…

Journal Article

Local Linear Forests

Rina Friedberg, Julie Tibshirani, Susan Athey, Stefan Wager
Journal of Computational and Graphical Statistics 2021 Vol. 30 Issue 2

Random forests are a powerful method for non-parametric regression, but are limited in their ability to fit smooth signals. Taking the perspective of random forests as an adaptive kernel method, we pair the forest kernel with a local linear…

Other Publication

Generic Drug Repurposing for Public Health and National Security: COVID-19 and Beyond

Rena Conti, Susan Athey, Richard Frank, Jonathan Gruber
Health Affairs December2020

The novel disease caused by the SARS-CoV-2 virus (COVID-19) has been a shock to both our health and wealth, with more than 276,000 dead in the U.S. and economic disruption that some have estimated as high as more than $16 trillion. These…

Working Paper

A How-To Guide for Conducting Retrospective Analyses: Example COVID-19 Study

Michael Powell, Allison Koenecke, James Brian Byrd, Akihiko Nishimura, Maximilian F. Konig, Ruoxuan Xiong, Sadiqa Mahmood, Vera Mucaj, Chetan Bettegowda, Liam Rose, Suzanne Tamang, Adam Sacarny, Brian Caffo, Susan Athey, Elizabeth A. Stuart, Joshua T. Vogelstein
September102020

In the urgent setting of the COVID-19 pandemic, treatment hypotheses abound, each of which requires careful evaluation. A randomized controlled trial generally provides the strongest possible evaluation of a treatment, but the efficiency and…

Working Paper

Alpha-1 Adrenergic Receptor Antagonists for Preventing Acute Respiratory Distress Syndrome and Death from Cytokine Storm Syndrome

Allison Koenecke, Michael Powell, Ruoxuan Xiong, Zhu Shen, Nicole Fischer, Sakibul Huq, Adham M. Khalafallah, Marco Trevisan, Pär Sparen, Juan J. Carrero, Akihiko Nishimura, Brian Caffo, Elizabeth A. Stuart, Renyuan Bai, Verena Staedtke, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein, Shibin Zhou, Chetan Bettegowda, Maximilian F. Konig, Brett Mensh, Joshua T. Vogelstein, Susan Athey
August2020

In severe viral pneumonia, including Coronavirus disease 2019 (COVID-19), the viral replication phase is often followed by hyperinflammation (‘cytokine storm syndrome’), which can lead to acute respiratory distress syndrome, multi-organ failure,…

Working Paper

Combining Experimental and Observational Data to Estimate Treatment Effects on Long Term Outcomes

Susan Athey, Raj Chetty, Guido W. Imbens
June172020

There has been an increase in interest in experimental evaluations to estimate causal effects, partly because their internal validity tends to be high. At the same time, as part of the big data revolution, large, detailed, and representative,…

Journal Article

policytree: Policy Learning via Doubly Robust Empirical Welfare Maximization over Trees

Erik Sverdrup, Ayush Kanodia, Zhengyuan Zhou, Susan Athey, Stefan Wager
The Journal of Open Source Software June2020 Vol. 5 Issue 50

The problem of learning treatment assignment policies from randomized or observational data arises in many fields. For example, in personalized medicine, we seek to map patient observables (like age, gender, heart pressure, etc.) to a treatment…

Journal Article

The Allocation of Decision Authority to Human and Artificial Intelligence

Susan Athey, Kevin A. Bryan, Joshua S. Gans
AEA Papers and Proceedings May2020 Vol. 110

The allocation of decision authority by a principal to either a human agent or an artificial intelligence is examined. The principal trades off an AI’s more aligned choice with the need to motivate the human agent to expend effort in learning…

Journal Article

Stable Prediction with Model Misspecification and Agnostic Distribution Shift

Kun Kuang, Ruoxuan Xiong, Peng Cui, Susan Athey, Bo Li
Association for the Advancement of Artificial Intelligence April32020

For many machine learning algorithms, two main assumptions are required to guarantee performance. One is that the test data are drawn from the same distribution as the training data, and the other is that the model is correctly specified. In real…

Journal Article

SHOPPER: A Probabilistic Model of Consumer Choice with Substitutes and Complements

Susan Athey, Francisco J. R. Ruiz, David M. Blei
Annals of Applied Statistics March2020 Vol. 14 Issue 1

We develop SHOPPER, a sequential probabilistic model of shopping data. SHOPPER uses interpretable components to model the forces that drive how a customer chooses products; in particular, we designed SHOPPER to capture how items interact with…

Journal Article

Sampling-based vs. Design-based Uncertainty in Regression Analysis

Alberto Abadie, Susan Athey, Guido W. Imbens, Jeffrey M. Wooldridge
Econometrica January12020 Vol. 88 Issue 1

Consider a researcher estimating the parameters of a regression function based on data for all 50 states in the United States or on data for all visits to a website. What is the interpretation of the estimated parameters and the standard errors?…

Journal Article

Economists (and Economics) in Tech Companies

Susan Athey, Michael Luca
Journal of Economic Perspectives December2019 Vol. 33 Issue 1

As technology platforms have created new markets and new ways of acquiring information, economists have come to play an increasingly central role in tech companies-tackling problems such as platform design, strategy, pricing, and policy. Over the…

Working Paper

Sufficient Representations for Categorical Variables

Jonathan Johannemann, Vitor Hadad, Susan Athey, Stefan Wager
August2019

Many learning algorithms require categorical data to be transformed into real vectors before it can be used as input. Often, categorical variables are encoded as one-hot (or dummy) vectors. However, this mode of representation can be…

Journal Article

Balanced Linear Contextual Bandits

Maria Dimakopoulou, Zhengyuan Zhou, Susan Athey, Guido W. Imbens
Proceedings of the AAAI Conference on Artificial Intelligence July232019 Vol. 33 Issue 1

Contextual bandit algorithms are sensitive to the estimation method of the outcome model as well as the exploration method used, particularly in the presence of rich heterogeneity or complex outcome models, which can lead to difficult estimation…

Working Paper

Synthetic Difference in Differences

Dmitry Arkhangelsky, Susan Athey, David A. Hirshberg, Guido W. Imbens, Stefan Wager
February12019

We present a new perspective on the Synthetic Control (SC) method as a weighted least squares regression estimator with time fixed effects and unit weights. This perspective suggests a generalization with two way (both unit and time) fixed…

Journal Article

Generalized Random Forests

Susan Athey, Julie Tibshirani, Stefan Wager
Annals of Statistics 2019 Vol. 47 Issue 2

We propose generalized random forests, a method for nonparametric statistical estimation based on random forests (Breiman [Mach. Learn. 45(2001) 5–32]) that can be used to fit any quantity of interest identified as…

Working Paper

Estimation Considerations in Contextual Bandits

Maria Dimakopoulou, Susan Athey, Guido W. Imbens
December2018

Contextual bandit algorithms are sensitive to the estimation method of the outcome model as well as the exploration method used, particularly in the presence of rich heterogeneity or complex outcome models, which can lead to difficult…

Working Paper

Offline Multi-Action Policy Learning: Generalization and Optimization

Susan Athey, Zhengyuan Zhou, Stefan Wager
October102018

In many settings, a decision-maker wishes to learn a rule, or policy, that maps from observable characteristics of an individual to an action. Examples include selecting offers, prices, advertisements, or emails to send to consumers, as well as…

Journal Article

Estimating Heterogeneous Consumer Preferences for Restaurants and Travel Time Using Mobile Location Data

Susan Athey, David Blei, Robert Donnelly, Francisco Ruiz, Tobias Schmidt
American Economic Review Papers and Proceedings May2018 Vol. 108

We estimate a model of consumer choices over restaurants using data from several thousand anonymous mobile phone users. Restaurants have latent characteristics (whose distribution may depend on restaurant observables) that affect consumers’ mean…

Journal Article

Approximate Residual Balancing: Debiased Inference of Average Treatment Effects in High Dimensions

Susan Athey, Guido W. Imbens, Stefan Wager
Journal of the Royal Statistical Society-Series B February182018 Vol. 80 Issue 4

There are many settings where researchers are interested in estimating average treatment effects and are willing to rely on the unconfoundedness assumption, which requires that the treatment assignment be as good as random conditional on…

Journal Article

Stable Predictions across Unknown Environments

Kun Kuang, Ruoxuan Xiong, Peng Cui, Susan Athey, Bo Li
Knowledge Discovery and Data Mining 2018

In many important machine learning applications, the training distribution used to learn a probabilistic classifier differs from the testing distribution on which the classifier will be used to make predictions. Traditional methods correct the…

Journal Article

Exact P-values for Network Interference

Susan Athey, Dean Eckles, Guido W. Imbens
Journal of the American Statistical Association November132017 Vol. 113 Issue 521

We study the calculation of exact p-values for a large class of non-sharp null hypotheses about treatment effects in a setting with data from experiments involving members of a single connected network. The class includes null hypotheses that…

Working Paper

Sampling-Based vs. Design-Based Uncertainty in Regression Analysis

Alberto Abadie, Susan Athey, Guido W. Imbens, Jeffrey M. Wooldridge
June2017

Previously titled: Finite Population Causal Standard Errors

Consider a researcher estimating the parameters of a regression function based on data for all 50 states in the United States or on data for all visits to a website. What…